Role Models Needed

Wermuth Comment : Are Marginal Models Needed ?

Operational models of allosteric modulation: caution is needed.

How female education reduces fertility: models and needed research.

Although the correlation between female education and fertility has been documented, the operators that link greater female education to lower fertility at either the individual or aggregate levels have not been specified or submitted to systematic empirical tests. Discovering which aspects of female education account for reduced fertility requires a refined conceptualization of the education-...

Preclinical models: needed in translation? A Pro/Con debate.

The discovery of the causative mutations and many of the predisposing risk factors for neurodegenerative disorders such as Amyotrophic Lateral Sclerosis, Alzheimer's, Parkinson's, and Huntington's disease (HD), has led to the development of a large number of genetic animal models of disease. In the case of HD, for example, over 20 different transgenic rodent models have been generated. These mo...

Needed Computations Shortcutting Needed Steps

We define a compilation scheme for a constructor-based strongly-sequential graph rewriting system which shortcuts some needed steps. The object code, what the compiler produces on input the rewriting system, is another constructor-based graph rewriting system that is normalizing for the original system when using an innermost strategy. Hence, the object code can be easily implemented by eager f...